Article

Suppression of epithelial proliferation and tumourigenesis by immunoglobulin A

2023-10-10

Abstract excerpt

Immunoglobulin A (IgA) is the most abundant antibody isotype produced across mammals and plays a specialized role in mucosal homeostasis 1 . Constantly secreted into the lumen of the intestine, IgA binds commensal microbiota to regulate their colonization and function 2,3 with unclear implications for health. IgA deficiency is common in humans but is difficult to study due to its complex aetiology and comorbidit...

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Literature Corpus work: d86e07a4-d3f6-524d-a529-c40e06ad2302
DOI: 10.1101/2023.10.06.561290

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