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Distinct Pulmonary Innate and Adaptive Immune Responses during the Initiation and Resolution of Natural and Breakthrough SARS-CoV-2 Infection

2025-10-21

Abstract excerpt

<title>Abstract</title> <p>The evolution of pulmonary immune responses in breakthrough and natural SARS-CoV-2 infection was evaluated with sequential single-cell profiling of bronchoalveolar cells from 11 vaccinated and 8 unvaccinated patients during the acute and recovery phases of their illness. Longitudinal mapping of lung cell transcriptome, proteome, and immune receptor repertoire resolved distinct phenotypi...

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Literature Corpus work
821dcd20-4906-5fe8-906d-17451d634e2e
DOI
10.21203/rs.3.rs-7716872/v1
Open publication

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Distinct Pulmonary Innate and Adaptive Immune Responses during the Initiation and Resolution of Natural and Breakthrough SARS-CoV-2 InfectionDOI 10.21203/rs.3.rs-7716872/v1
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