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A Pan-Cancer Analysis of the Oncogenic Role of Integrin Beta4 (ITGB4) in Human Tumors

1 Dec 2021

Abstract excerpt

BACKGROUND: Integrin beta4 (ITGB4) is a transmembrane receptor that plays a key role in tumorigenesis and tumor development. However, there are no pan-cancer analyses of ITGB4. METHODS: This study demonstrates the first potential oncogenic roles of ITGB4 across 33 tumors based on the dataset of the Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO). RESULTS: ITGB4 is highly expressed in many cancers,...

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PMID: 34924769
DOI: 10.2147/ijgm.s341076

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