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Molecular typing of gliomas on the basis of integrin family genes and a functional study of ITGA7

10 Apr 2025

Abstract excerpt

Gliomas are highly malignant tumors of the central nervous system, and their complex molecular heterogeneity poses major therapeutic challenges. Integrins are important members of the class of cell adhesion molecules (CAMs), consisting of α-subunits and β-subunits that form 24 different heterodimers. To elucidate the complex role of integrins in glioma pathogenesis, we analyzed integrin family genes. We used a...

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PMID: 40210748
DOI: 10.1038/s41598-025-97342-3

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