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ERCC1 and ERCC2 genes expression and their SNPs variants identify a favorable signature for SCLC patients treated with platinum-based chemotherapy

2023-10-10

Abstract excerpt

<h4>Background: </h4> Platinum chemotherapy (CT) remains the backbone of systemic therapy for patients with small-cell lung cancer (SCLC). The nucleotide excision repair (NER) pathway plays a central role in the repair of the DNA damages exerted by platinum agents. Alteration in this repair mechanism may affect patients survival. <h4>Methods: </h4>: We retrospectively collected data from 38 patients with extended...

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Literature Corpus work
d7fa962c-288d-56e6-8644-41751d29e6e8
DOI
10.21203/rs.3.rs-3409611/v1
Open publication

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ERCC1 and ERCC2 genes expression and their SNPs variants identify a favorable signature for SCLC patients treated with platinum-based chemotherapyDOI 10.21203/rs.3.rs-3409611/v1
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