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Article

Role of ERCC5 promoter polymorphisms in response to platinum-based chemotherapy in patients with advanced non-small-cell lung cancer.

Anti-cancer drugs - 1 Mar 2013

He Caiyun, Duan Zhipeng, Li Ping, Xu Qian, Yuan Yuan

Abstract excerpt

The ERCC5 gene plays an important role in the nucleotide excision repair pathway that recognizes and removes platinum-DNA adducts. We aimed to examine whether ERCC5 promoter polymorphisms contribute toward intervariations in the platinum treatment response in patients with advanced non-small-cell lung cancer (NSCLC). We evaluated the association between three tag-single nucleotide polymorphisms in the ERCC5...

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Source

Identifiers

PMID: 23211354
DOI: 10.1097/CAD.0b013e32835bd6ce

Genes

ERCC5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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