Article
Proteomic organ-specific signatures, ageing traits, disease risks and genetic architecture in an East Asian population.
EBioMedicine - 1 Aug 2026
Bennett Derrick A, Wang Baihan, Xiao Sihao, Wright Neil, Edris Ahmed, Wang Yunhe, Millwood Iona Y, Walters Robin G, Du Huaidong, Yang Ling, Chen Yiping, Avery Daniel, Schmidt Dan Valle, Yu Canqing, Sun Dianjianyi, Lv Jun, Hill Michael, Li Liming, Clarke Robert, Chen Zhengming
Abstract excerpt
BACKGROUND: Protein-based ageing clocks can be used to help identify individuals at high risk of death or morbidity. There is a lack of evidence in non-European populations on clocks derived from combining different proteomic platforms and their relationship with age-related traits, diseases and genetic architecture. METHODS: The prospective China Kadoorie Biobank assayed proteins via Olink and SomaScan in ∼4000...
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