Article

Subcellular transcriptome of radial glia reveals compartmentalized control of cortical development

2025-10-10

Abstract excerpt

RNA localization and local translation mediate spatial and temporal control of polarized cells, including radial glial cells (RGCs) which produce and organize neurons and glia. Within RGCs, RNAs are transported long distances to basal endfeet, where they can undergo local translation. However, the subcellular composition of RGCs and function of local gene regulation remains largely unknown. Here, we discover that...

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Literature Corpus work: d7acebd1-0f23-59d8-acde-e9fe3e99a0df
DOI: 10.1101/2025.10.10.679263

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