Article

Organelle distribution and protein translation defects in radial glia cells with mutations in Eml1

2025-12-26

Abstract excerpt

Cerebral cortical development is a finely regulated process, depending on key neuronal progenitors, giving rise to post-mitotic neurons that migrate to superficial regions in the developing brain. Disruptions can give rise to severe cortical malformations that are associated with intellectual disability and intractable epilepsy. Mutations in EML1/Eml1 , coding for a microtubule (MT)-associated protein, lead to su...

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Literature Corpus work: 7c945be9-4d7a-5f3f-a9e7-b5d5df2a0812
DOI: 10.64898/2025.12.24.696387

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