Article

Drug prediction for reversing AD/PD transcriptional profiles using an aging of systems-centric approach

2022-11-02

Abstract excerpt

Age-related pathologies are so widely presented in old age that in most cases they are hardly distinguishable at the molecular level from the so-called ‘‘normal’’ aging. Both aging and age-related diseases are characterized by a wide range of transcriptional and epigenetic changes that underlie the physiological or pathological phenotype, with plenty of overlap in their signatures, but also with differences. In mo...

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Literature Corpus work: d79d1ab0-b973-5e34-a296-fc74dcf6428c
DOI: 10.1101/2022.11.01.514657

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