Article
The effect of photoreceptor degeneration on ganglion cell morphology.
The Journal of comparative neurology - 1 Apr 2014
O'Brien E E, Greferath U, Fletcher E L
Abstract excerpt
Retinitis pigmentosa refers to a family of inherited photoreceptor degenerations resulting in blindness. During and after photoreceptor loss, neurons of the inner retina are known to undergo plastic changes. Here, we have investigated in detail whether ganglion cells are altered at late stages of degeneration, well after the total loss of photoreceptors. We used mice, rd1-Thy1, that carry a mutation in the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.