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Article

Molecular mechanisms underlying inherited photoreceptor degeneration as targets for therapeutic intervention

2 Feb 2024

Abstract excerpt

Retinitis pigmentosa (RP) is a form of retinal degeneration characterized by primary degeneration of rod photoreceptors followed by a secondary cone loss that leads to vision impairment and finally blindness. This is a rare disease with mutations in several genes and high genetic heterogeneity. A challenging effort has been the characterization of the molecular mechanisms underlying photoreceptor cell death...

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PMID: 38370034
DOI: 10.3389/fncel.2024.1343544

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