Article

Gene gain and loss drive the diversification of gig immune genes in teleosts: structural and regulatory insights from Atlantic salmon

2025-07-05

Abstract excerpt

Interferon-stimulated genes (ISGs) are key players in vertebrate antiviral immunity. Among teleost ISGs, the grass carp reovirus-induced gene ( gig ) families 1 and 2 ( gig1 and gig2 , respectively) are absent in mammals but conserved in fishes and amphibians, and they have been implicated in resistance to viral infections across several aquaculture species. In particular, gig1 and gig2 genes are transcriptio...

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Literature Corpus work: d77bb9cd-5595-5c30-8fc6-248b67b02b7c
DOI: 10.1101/2025.07.01.662619

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