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Article

Genome-Wide Characterization of Zebrafish Endogenous Retroviruses Reveals Unexpected Diversity in Genetic Organizations and Functional Potentials.

Microbiology spectrum - 22 Dec 2021

Bai Jun, Yang Zuo-Zhen, Li Hao, Hong Yun, Fan Dong-Dong, Lin Ai-Fu, Xiang Li-Xin, Shao Jian-Zhong

Abstract excerpt

Endogenous retroviruses (ERVs) occupy a substantial fraction of mammalian genomes. However, whether ERVs extensively exist in ancient vertebrates remains unexplored. Here, we performed a genome-wide characterization of ERVs in a zebrafish (Danio rerio) model. Approximately 3,315 ERV-like elements (DrERVs) were identified as Gypsy, Copia, Bel, and class I-III groups. DrERVs accounted for approximately 2.3% of...

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Identifiers

PMID: 34908463
DOI: 10.1128/spectrum.02254-21
PMCID: PMC8672886

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