Article

Characterization of Anti-Phospholipid Antibodies in Lyme Borreliosis Using In-House Developed ELISAs

2026-05-20

Abstract excerpt

<h4>Objectives: </h4> Borrelia burgdorferi sensu lato, a spirochete bacterium responsible for Lyme borreliosis - the most common tick-borne infection in North America and Europe - can trigger the production of antiphospholipid antibodies. These antibodies target host lipids such as cardiolipin (CL), phosphatidic acid (PA), phosphatidylcholine (PC), and phosphatidylserine (PS), which the spirochete incorporates int...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d76146c1-c06c-588e-8dfb-a8906b5ab534
DOI: 10.20944/preprints202605.1358.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Characterization of Anti-Phospholipid Antibodies in Lyme Borreliosis Using In-House Developed ELISAsDOI 10.20944/preprints202605.1358.v1Read

Lipoproteome screening of the Lyme disease agent identifies novel inhibitors of antibody-mediated complement killingSemantic proximity Read

PCR in laboratory diagnosis of human Borrelia burgdorferi infectionsSemantic proximity Read

Redefining serological diagnostics with immunoaffinity proteomicsSemantic proximity Read

Multiplexed single-tier immunoassay for improved Lyme disease diagnosis across all disease stagesSemantic proximity Read

A customizable multiplex protein microarray for antibody testing and its application for tick-borne and other infectious diseasesSemantic proximity Read

Serologic Response to Borrelia Antigens Varies with Clinical Phenotype in Children and Young Adults with Lyme Disease.Semantic proximity Read

Chemiluminescence Immunoassay and Enzyme-Linked Immunosorbent Assay in the Diagnosis of Autoimmune Bullous Diseases: A Comparative StudySemantic proximity Read

UHPLC-MS/MS-based untargeted metabolite profiling of Lyme neuroborreliosisSemantic proximity Read

Fluorescent bead–based multiplex assays improve serological disease diagnostics and have potential of identifying sensitive immune biomarkers for maintaining health and performanceSemantic proximity Read

Profiling the humoral immune response to Borrelia burgdorferi infection with protein microarraysSemantic proximity Read

Complement therapeutic Factor H-IgG proteins as pre-exposure prophylaxes against Lyme borreliae infectionsSemantic proximity Read

<i>Borrelia burgdorferi</i> peptidoglycan is a persistent antigen in patients with Lyme arthritisSemantic proximity Read