Article

Complement therapeutic Factor H-IgG proteins as pre-exposure prophylaxes against Lyme borreliae infections

2024-09-26

Abstract excerpt

<h4>ABSTRACT</h4> Lyme disease (LD) is the most common vector-borne disease in the northern hemisphere and is caused by the bacteria Borrelia burgdorferi sensu lato (also known as Lyme borreliae) with no effective prevention available. Lyme borreliae evade complement killing, a critical arm of host immune defense, by producing outer surface proteins that bind to a host complement inhibitor, factor H (FH). These...

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Literature Corpus work: 0a4079fe-c4a1-5622-9158-a96f29d11735
DOI: 10.1101/2024.09.26.615144

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