Article

Multiplexed single-tier immunoassay for improved Lyme disease diagnosis across all disease stages

2026-02-09

Abstract excerpt

<title>Abstract</title> <p>Lyme disease is the most common vector-borne infection in North America and Europe, yet current two-tier serologic testing shows poor sensitivity during early infection when antibiotic treatment is most effective. We developed and validated a single-tier multiplex immunoassay that combines ten Borrelia burgdorferi antigens with machine-learning classification to detect antibody response...

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Literature Corpus work: 1b2148fa-6686-5ac0-b31c-68a65e6ec699
DOI: 10.21203/rs.3.rs-8502997/v1

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