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Molecular Targeted Therapy for Hepatocellular Carcinoma: Present Status and Future Directions

1 Jan 2015

Abstract excerpt

Hepatocellular carcinoma (HCC) is the sixth most common cancer and the third most lethal neoplasm, causing an estimated 700000 deaths annually. Currently HCC has only one systemic molecular targeted therapy, the multi-kinase inhibitor, sorafenib. The standard-of-care for advanced liver cancer is limited because sorafenib can expand the median life expectancy of patients for only 1 year. Thus there is an urgent...

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PMID: 26133708
DOI: 10.1248/bpb.b15-00231

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