Article
Chromatin Accessibility Contributes to <em>Candida albicans</em> Adaptation to Echinocandins
2024-12-25
Abstract excerpt
Infections by the major opportunistic pathogen of human Candida albicans are commonly treated with echinocandin (ECN) drugs. However, C. albicans can adapt to grow in the presence of certain amounts of ECNs. Prior studies by several laboratories have defined multiple genes, as well as mechanisms involving induced aneuploidy, that can govern this. Still, mechanisms of ECN adaptation are not fully understood. Here,...
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Identifiers and source
- Literature Corpus work
- d7040379-0fe8-5db5-9ce2-c5ec3dde2f10
- DOI
- 10.20944/preprints202412.2205.v1
