Article
Macrophage heterogeneity and differentiation: defined serum-free culture conditions induce different types of macrophages in vitro.
Research in immunology - 1 Jan 1992
Kreutz M, Krause S W, Hennemann B, Rehm A, Andreesen R
Abstract excerpt
Macrophages (MAC) are important effector cells of the immune system. They arise from circulating blood monocytes (MO), which undergo further maturation upon leaving the vasculature and migrating into the various tissues and body cavities. A similar differentiation process can be followed in vitro when monocytes are cultured in the presence of serum. In this study, different factors and serum proteins, either...
Topics
- Antigens, Differentiation
- Blood Proteins
- Calcitriol
- Cell Differentiation
- Culture Media
- Cytological Techniques
- Humans
- In Vitro Techniques
- Macrophage Colony-Stimulating Factor
- Macrophages
- Phenotype