Article

Single-Cell and Mendelian Analyses Reveal Shared Mechanisms Between Head and Neck Neoplasms and Aging

2025-08-08

Abstract excerpt

<title>Abstract</title> <p><bold>Objective: </bold>This study aims to explore shared key genes between head and neck neoplasm (HNN) and aging. <bold>Methods:</bold>Using single-cell RNA sequencing data of peripheral blood from HNN patients, aging individuals, and healthy controls, we identified cross-group co-expressed, downregulated cell subpopulations as core targets. Integrated pseudotime trajectory analysis a...

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Literature Corpus work: d6728df2-e637-5467-bef1-643ad860c100
DOI: 10.21203/rs.3.rs-7113655/v1

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