Article

Comprehensive analysis of Mendelian randomization and single-cell sequencing reveals the causal relationship between intrahepatic cholangiocarcinoma and chronotype-related genes

2023-11-29

Abstract excerpt

<h4>Background: </h4> The tumor development is related to disruption of circadian rhythms. However, the causal relationship between chronotype and intrahepatic cholangiocarcinoma (ICC) and molecular mechanism of chronotype-related genes (CRGs) are vague. Methods Genetic summary statistics were obtained from the Integrative Epidemiology Unit (IEU) OpenGWAS and genome-wide association studies (GWAS) Catalog. Univar...

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Literature Corpus work: 121e9834-14ec-5886-ac02-427cca1368af
DOI: 10.21203/rs.3.rs-3658369/v1

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