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Aging and head and neck cancer insights from single cell and spatial transcriptomic analyses

18 Dec 2024

Abstract excerpt

BACKGROUND: Head and neck squamous cell carcinoma(HNSCC) is the sixth most common malignancy worldwide, with more than 890,000 new cases and 450,000 deaths annually. Its major risk factors include smoking, alcohol abuse, aging, and poor oral hygiene. Due to the lack of early and effective detection and screening methods, many patients are diagnosed at advanced stages with a five-year survival rate of less than...

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PMID: 39692961
DOI: 10.1007/s12672-024-01672-z

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