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Integrative Single-Cell and Multi-Cohort Analysis of the Netrin-1 Signaling Pathway Reveals Divergent Prognostic Trends and Sex-Dimorphic Associations in Glioblastoma

2026-05-20

Abstract excerpt

<h4>Background</h4> The Netrin-1 dependence receptor pathway plays critical roles in neural development, but its expression landscape and prognostic significance in glioblastoma (GBM) remain poorly characterized. <h4>Methods</h4> Single-cell RNA-seq data from 148,019 cells across 34 tumors (Neftel et al., 2019) were analyzed to map Netrin-1 pathway gene expression across GBM cellular states. Differential gene ex...

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Literature Corpus work
b25f8011-6fc7-5eb8-b134-1ea240ae7167
DOI
10.64898/2026.05.17.725695
Open publication

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Integrative Single-Cell and Multi-Cohort Analysis of the Netrin-1 Signaling Pathway Reveals Divergent Prognostic Trends and Sex-Dimorphic Associations in GlioblastomaDOI 10.64898/2026.05.17.725695
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