Article

Enabling FIB-SEM Systems for Large Volume Connectomics and Cell Biology

2019-11-25

Abstract excerpt

Isotropic high-resolution imaging of large volumes provides unprecedented opportunities to advance connectomics and cell biology research. Conventional Focused Ion Beam Scanning Electron Microscopy (FIB-SEM) offers unique benefits such as high resolution (< 10 nm in x, y, and z), robust image alignment, and minimal artifacts for superior tracing of neurites. However, its prevailing deficiencies in imaging speed an...

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Literature Corpus work: d654770a-3e8b-5a05-b77e-4cd98c1c727a
DOI: 10.1101/852863

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