Article

Volume electron microscopy reveals 3D synaptic nanoarchitecture in postmortem human prefrontal cortex

2024-02-28

Abstract excerpt

<h4>SUMMARY</h4> Synaptic function is directly reflected in quantifiable ultrastructural features using electron microscopy (EM) approaches. This coupling of synaptic function and ultrastructure suggests that in vivo synaptic function can be inferred from EM analysis of ex vivo human brain tissue. To investigate this, we employed focused ion beam-scanning electron microscopy (FIB-SEM), a volume EM (VEM) approac...

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Literature Corpus work: 810ef198-84cf-5400-942d-3e042878232c
DOI: 10.1101/2024.02.26.582174

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