Article

Mimicking opioid analgesia in cortical pain circuits

2024-04-29

Abstract excerpt

The anterior cingulate cortex is a key brain region involved in the affective and motivational dimensions of pain, yet how opioid analgesics modulate this cortical circuit remains unclear. Uncovering how opioids alter nociceptive neural dynamics to produce pain relief is essential for developing safer and more targeted treatments for chronic pain. Here we show that a population of cingulate neurons encodes spontan...

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Identifiers and source

Literature Corpus work: d61d7b00-6a25-5dbc-a68c-fa249685fc25
DOI: 10.1101/2024.04.26.591113

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