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Efficacy and Safety of Chimeric Antigen Receptor T-Cell Therapy in Children, Adolescents, and Young Adults with Relapsed or Refractory Solid Tumors: A Systematic Review and Meta-Analysis

2026-08-07

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<title>Abstract</title> <p>Purpose Chimeric antigen receptor T-cell (CAR-T) therapy has shown remarkable success in pediatric hematological malignancies, but its efficacy and safety in pediatric and adolescent solid tumors have not been systematically evaluated. This meta-analysis aimed to assess the antitumor activity and toxicity of CAR-T therapy in this population. Methods Two independent reviewers systemati...

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Literature Corpus work
d5f21cca-f679-5c88-91a3-4a543a2fc768
DOI
10.21203/rs.3.rs-10543543/v1
Open publication

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Efficacy and Safety of Chimeric Antigen Receptor T-Cell Therapy in Children, Adolescents, and Young Adults with Relapsed or Refractory Solid Tumors: A Systematic Review and Meta-AnalysisDOI 10.21203/rs.3.rs-10543543/v1
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