Article

A meta-analysis on safety and efficacy of CD19 directed CAR T-cells generated using sleeping beauty transposon system

2024-07-23

Abstract excerpt

<title>Abstract</title> Chimeric antigen receptor (CAR) T-cell therapy has emerged as a potentially curative approach for hematological malignancies. The sleeping beauty (SB) transposon system represents a non-viral approach to CAR T-cell generation offering several advantages including low immunogenicity, scalability, and cost-effectiveness over existing methods. Despite significant clinical advances, the eff...

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Literature Corpus work: 1eec5918-00fa-5d38-85d9-53e0bdc9d972
DOI: 10.21203/rs.3.rs-4621884/v1

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