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Chimeric Antigen Receptor Based Cellular Therapy for Treatment Of T-Cell Malignancies

6 May 2022

Abstract excerpt

T-cell malignancies can be divided into precursor (T-acute lymphoblastic leukemia/lymphoblastic lymphoma, T-ALL/LBL) and mature T-cell neoplasms, which are comprised of 28 different entities. Most of these malignancies are aggressive with rather poor prognosis. Prognosis of relapsed/refractory (R/R) disease is especially dismal, with an expected survival only several months after progression. Targeted therapies,...

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PMID: 35600381
DOI: 10.3389/fonc.2022.876758

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