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Proteome-wide multipoint internal calibration curves for mass spectrometry-based quantitative proteomics

2025-02-28

Abstract excerpt

Mass spectrometry (MS)-based proteomics is known for its high accuracy in quantifying peptides and proteins using various calibration strategies, including internal and external calibration curves. While external multi-point calibration curves are created from serial dilutions, they often fail to account for sample-specific matrix effects. In contrast, internal calibration curves account for sample matrix but face...

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Literature Corpus work
d5e113fb-21db-5f20-aff0-dd73fb8658e7
DOI
10.1101/2025.02.24.639845
Open publication

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Proteome-wide multipoint internal calibration curves for mass spectrometry-based quantitative proteomicsDOI 10.1101/2025.02.24.639845
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