Article
Analytical error reduction using single point calibration for accurate and precise metabolomic phenotyping.
Journal of proteome research - 1 Nov 2009
van der Kloet Frans M, Bobeldijk Ivana, Verheij Elwin R, Jellema Renger H
Abstract excerpt
Analytical errors caused by suboptimal performance of the chosen platform for a number of metabolites and instrumental drift are a major issue in large-scale metabolomics studies. Especially for MS-based methods, which are gaining common ground within metabolomics, it is difficult to control the analytical data quality without the availability of suitable labeled internal standards and calibration standards even...
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