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Multiplexed triage of candidate biomarkers in plasma using internal standard triggered-parallel reaction monitoring mass spectrometry

2021-09-03

Abstract excerpt

Despite advances in proteomic technologies, clinical translation of plasma biomarkers remains low, partly due to a major bottleneck between the discovery of candidate biomarkers and downstream costly clinical validation studies. Due to a dearth of multiplexable assays, generally only a few candidate biomarkers are tested, and the validation success rate is accordingly low. Here, we demonstrate the capability of in...

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Identifiers and source

Literature Corpus work
26fe8734-550f-5387-a2fd-a2f954cf8589
DOI
10.1101/2021.09.02.458791
Open publication

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Multiplexed triage of candidate biomarkers in plasma using internal standard triggered-parallel reaction monitoring mass spectrometryDOI 10.1101/2021.09.02.458791
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