Article

Altered Mechanobiology of PDAC Cells with Acquired Chemoresistance to Gemcitabine and Paclitaxel

2024-04-13

Abstract excerpt

<h4>Background</h4> Pancreatic ductal adenocarcinoma (PDAC) acquired resistance to chemotherapy poses a major limitation to patient survival. Despite understanding of some biological mechanisms of chemoresistance, much of those mechanisms remain to be uncovered. Mechanobiology, which studies physical properties of cells, holds promise as a potential target for addressing challenges of chemoresistance in PDAC. The...

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Literature Corpus work: d5d27894-b5ce-5c1f-ae50-b3c05bc01fb5
DOI: 10.1101/2024.04.10.588671

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