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Article

Cellular mechanobiology and cancer metastasis

1 Dec 2007

Abstract excerpt

The primary cause of cancer treatment failure is invasion and metastasis, and invading tumor cells utilize many of the motility patterns that have been documented for normal morphogenesis. Recently, the role of mechanical forces in guiding various tissue and cell movements in embryonic development has been systematically analyzed with new experimental and computational methods. The tissue and cellular...

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PMID: 18228263
DOI: 10.1002/bdrc.20110

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