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Repurposing of Human Kinase Inhibitors in Neglected Protozoan Diseases

7 Jun 2017

Abstract excerpt

Human African trypanosomiasis (HAT), Chagas disease, and leishmaniasis belong to a group of infectious diseases known as neglected tropical diseases and are induced by infection with protozoan parasites named trypanosomatids. Drugs in current use have several limitations, and therefore new candidate drugs are required. The majority of current therapeutic trypanosomatid targets are enzymes or cell-surface...

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PMID: 28590590
DOI: 10.1002/cmdc.201700259

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