Article

Investigating the genetic factors of medication dosing using biobank-linked drug purchase data

2025-04-03

Abstract excerpt

<h4>ABSTRACT</h4> Despite significant pharmacogenomic (PGx) insights into key biological pathways influencing drug response, the polygenic contribution to dose variability and the potential of electronic health records (EHRs) for maintenance dose estimation remain largely unexplored. To address this gap, we leveraged longitudinal drug purchase data from the Estonian Biobank to derive medication dose metrics and in...

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Literature Corpus work: d5a28d89-c4ce-5b6a-87ab-5c7f640e577b
DOI: 10.1101/2025.04.01.25325019

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