Article

A single transcriptional regulator is crucial for the adaptation of <i>Staphylococcus aureus</i> to diverse niches

2025-08-01

Abstract excerpt

The adaptation of versatile multi-host pathogens to various hosts and various niches within hosts is often still poorly understood. The alternative Sigma factor B (SigB) is the master regulator of the general stress response of most gram-positive bacteria, which is a classic case of adaptive plasticity. In Staphylococcus aureus , SigB appears co-opted to function as a switch between intracellular and extracellula...

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Literature Corpus work: d59b16bb-cb49-58f7-8d80-cc51072be0ba
DOI: 10.1101/2025.08.01.668060

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