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Niche-specific genome degradation and convergent evolution shaping <i>Staphylococcus aureus</i> adaptation during severe infections

2022-02-12

Abstract excerpt

<h4>ABSTRACT</h4> During severe infections, Staphylococcus aureus moves from its colonising sites to blood and tissues, and is exposed to new selective pressures, thus potentially driving adaptive evolution. Previous studies have shown the key role of the agr locus in S. aureus pathoadaptation, however a more comprehensive characterisation of genetic signatures of bacterial adaptation may enable prediction of...

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Literature Corpus work
205e6cb0-3ddc-5901-a117-cfa5b92d2ab8
DOI
10.1101/2022.02.11.480068
Open publication

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