Article

A hierarchical regulatory cascade defines the temporal window of natural transformation in <i>Staphylococcus aureus</i>

2026-08-04

Abstract excerpt

Natural transformation (NT), a major mechanism of horizontal gene transfer, promotes bacterial genome plasticity and contributes to the dissemination of antibiotic resistance. NT requires the development of competence, a transient and tightly regulated physiological state that is induced by environmental cues. Although competence has recently been demonstrated in the human pathogen Staphylococcus aureus , the reg...

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Literature Corpus work: 1e2a1b80-119a-5fc2-870b-f387e4d55623
DOI: 10.64898/2026.08.03.742410

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