Article

Activation of the EGFR-PI3K-CaM Pathway by PRL-1 Ameliorates Liver Cirrhosis via ER Stress-dependent Calcium

2021-07-15

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Accumulation of cholesterol and depletion of calcium induce hepatic injury through the endoplasmic reticulum (ER) stress response. ER stress regulates the calcium imbalance between the ER and mitochondria. Previously, we reported that phosphatase of regenerating liver-1 (PRL-1)-overexpressing placenta-derived mesenchymal stem cells (PD-MSCs<sup>PRL-1</sup>) prom...

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Literature Corpus work: d58fcf52-8ddc-5d70-8e7d-30b0e56405c0
DOI: 10.21203/rs.3.rs-710155/v1

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