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Role of Sigma-1 Receptor in Calcium Modulation: Possible Involvement in Cancer

22 Jan 2021

Abstract excerpt

Ca2+ signaling plays a pivotal role in the control of cellular homeostasis and aberrant regulation of Ca2+ fluxes have a strong impact on cellular functioning. As a consequence of this ubiquitous role, Ca2+ signaling dysregulation is involved in the pathophysiology of multiple diseases including cancer. Indeed, multiple studies have highlighted the role of Ca2+ fluxes in all the steps of cancer progression. In...

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PMID: 33499031
DOI: 10.3390/genes12020139

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