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Ebola Virus Infection of Liver Cells: Effect of Interferon Gamma on Virus Infection of Primary Kupffer Cells and a Kupffer Cell Line

2023-08-29

Abstract excerpt

Ebola virus disease (EVD) represents a global health threat. The etiological agents of EVD are 6 species of Orthoebolaviruses, with Orthoebolavirus zairense (EBOV) having the greatest public health and medical significance. EVD disease pathogenesis occurs as a result of broad cellular tropism of the virus, robust viral replication and a potent and dysregulated production of cytokines. In vivo, tissue macrophages a...

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Literature Corpus work: d5875371-47e6-5be9-8a5b-9f4f8fa2b6e4
DOI: 10.20944/preprints202308.1977.v1

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