Article

Statistical Analysis Supports UTR（untranslated region）Deletion Theory in SARS-CoV-2

2021-10-15

Abstract excerpt

The statistical analysis found that the mortality rate of COVID-19 infection experienced a significant decline in the early stage of the epidemic. We suspect that the sharp deterioration of virus toxicity is related to point mutation and the deletion of the untranslated region of the virus genome. Through sequence analysis of mega-genome data, we found that the genome length of COVID-19 was deleted, which mainly o...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d583347e-f523-5fb0-95c4-9fcb0e647c8a
DOI: 10.21203/rs.3.rs-967894/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Statistical Analysis Supports UTR（untranslated region）Deletion Theory in SARS-CoV-2DOI 10.21203/rs.3.rs-967894/v1Read

RNA–RNA interactions between SARS-CoV-2 and host benefit viral development and evolution during COVID-19 infectionSemantic proximity Read

Consensus insertion/deletions and amino acid variations of all coding and noncoding regions of the SARS-CoV-2 Omicron clades, including the XBB and BQ.1 lineagesSemantic proximity Read

Achilles' Heel of SARS-CoV-2: Transcription Regulatory Sequence and Leader Sequence in 5’ Untranslated Region have Unique Evolutionary Patterns and are Vital for Virus Replication in Infected Human CellsSemantic proximity Read

A Transcription Regulatory Sequence in the 5′ Untranslated Region of SARS-CoV-2 Is Vital for Virus Replication with an Altered Evolutionary Pattern against Human Inhibitory MicroRNAsSemantic proximity Read

The highly conserved stem-loop II motif is dispensable for SARS-CoV-2Semantic proximity Read

Global cataloguing of variations in untranslated regions of viral genome and prediction of key host RNA binding protein-microRNA interactions modulating genome stability in SARS-CoV2Semantic proximity Read

Discovery of a 382-nt deletion during the early evolution of SARS-CoV-2Semantic proximity Read

Human SARS-CoV-2 has evolved to reduce CG dinucleotide in its open reading frames.Semantic proximity Read

How miRNAs can protect humans from coronaviruses COVID-19, SARS-CoV, and MERS-CoVSemantic proximity Read

Dynamic Zero-Covid strategy curtails mutagenesis and emergence of new variants of the SARS-CoV-2Semantic proximity Read

Aerodynamic Characteristics and RNA Concentration of SARS-CoV-2 Aerosol in Wuhan Hospitals during COVID-19 OutbreakSemantic proximity Read

Two deletion variants of Middle East respiratory syndrome coronavirus found in a patient with characteristic symptoms.Semantic proximity Read