Article

Discovery of a 382-nt deletion during the early evolution of SARS-CoV-2

2020-03-12

Abstract excerpt

To date, the SARS-CoV-2 genome has been considered genetically more stable than SARS-CoV or MERS-CoV. Here we report a 382-nt deletion covering almost the entire open reading frame 8 (ORF8) of SARS-CoV-2 obtained from eight hospitalized patients in Singapore. The deletion also removes the ORF8 transcription-regulatory sequence (TRS), which in turn enhances the downstream transcription of the N gene. We also found...

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Literature Corpus work: 1d73c798-22c8-585a-8945-d186fff3f11c
DOI: 10.1101/2020.03.11.987222

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