Article

The highly conserved stem-loop II motif is dispensable for SARS-CoV-2

2023-03-16

Abstract excerpt

<h4>ABSTRACT</h4> The stem-loop II motif (s2m) is a RNA structural element that is found in the 3’ untranslated region (UTR) of many RNA viruses including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Though the motif was discovered over twenty-five years ago, its functional significance is unknown. In order to understand the importance of s2m, we created viruses with deletions or mutations of the...

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Literature Corpus work: 3fef7722-49d5-5503-9da9-80658e005303
DOI: 10.1101/2023.03.15.532878

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