Article

Pathological expansion of gut microbiome-associated<i>Enterococcus</i>in advanced cirrhosis corresponds with multilevel perturbations of the gut-liver-immune axis

2025-02-14

Abstract excerpt

<h4>Background</h4> Chronic liver disease (CLD) is a progressive condition that can advance to cirrhosis and acute-on-chronic liver failure (ACLF), a syndrome characterised by multi-organ dysfunction, critical illness, and high mortality. ACLF is driven by systemic inflammation, often without overt infection, suggesting alternative immune activation pathways, including microbial translocation. While intestinal per...

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Literature Corpus work: 99c8667e-32b6-5bfb-81a8-b4086ee00caa
DOI: 10.1101/2025.02.13.25322003

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