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Article

PBMC transcriptomics identifies immune-metabolism disorder during the development of HBV-ACLF

11 Jan 2021

Abstract excerpt

OBJECTIVE: Hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) pathophysiology remains unclear. This study aims to characterise the molecular basis of HBV-ACLF using transcriptomics. METHODS: Four hundred subjects with HBV-ACLF, acute-on-chronic hepatic dysfunction (ACHD), liver cirrhosis (LC) or chronic hepatitis B (CHB) and normal controls (NC) from a prospective multicentre cohort were studied,...

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Identifiers

PMID: 33431576
DOI: 10.1136/gutjnl-2020-323395

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