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Genetic-epigenetic intersection in trophoblast differentiation: Implications for extraembryonic tissue function

1 Jan 2010

Abstract excerpt

Recent years have seen considerable advances in our understanding of early mammalian development leading up to the establishment of the first cell lineages, with important implications for the behavior of stem cells derived from the early embryo. Dramatic new insights have also propelled the field of epigenetics with the identification of 5-hydroxymethylcytosine as an additional base modification and the...

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PMID: 20083894
DOI: 10.4161/epi.5.1.10589

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