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Nab-paclitaxel fused with the <i>de novo</i> designed receptor binder exhibits enhanced tumor targeting and therapeutic efficacy

2026-01-30

Abstract excerpt

Chemotherapy has been widely used in cancer treatment, but most of the chemotherapeutic drugs rely mainly on passive accumulation due to lack of target specificity, which may lead to systemic toxicity and limited clinical utility. Recent advances in artificial intelligence-based protein design provide new opportunities for developing precision therapeutics. Here we modify the albumin-bound paclitaxel (Nab-PTX), on...

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Literature Corpus work
d53070fe-2666-5cc4-9636-929068a2c1d7
DOI
10.64898/2026.01.28.702218
Open publication

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Nab-paclitaxel fused with the <i>de novo</i> designed receptor binder exhibits enhanced tumor targeting and therapeutic efficacyDOI 10.64898/2026.01.28.702218
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